{"id":36202,"date":"2021-03-08T18:28:38","date_gmt":"2021-03-08T18:28:38","guid":{"rendered":"https:\/\/higeacbd.com\/oleos\/gpr55-um-terceiro-recetor-canabinoide\/"},"modified":"2025-03-24T12:05:47","modified_gmt":"2025-03-24T12:05:47","slug":"gpr55-um-terceiro-recetor-canabinoide","status":"publish","type":"post","link":"https:\/\/higeacbd.com\/pt-pt\/datos\/gpr55-um-terceiro-recetor-canabinoide","title":{"rendered":"GPR55: Um terceiro recetor canabin\u00f3ide?"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero” _builder_version=”4.9.1″ background_color=”rgba(255,255,255,0.65)” background_image=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/gpr55.jpg” background_blend=”soft-light” custom_padding=”3vw||1vw|||” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_cta title=”GPR55: Um terceiro recetor canabin\u00f3ide?” _builder_version=”4.9.0″ header_level=”h1″ header_font=”|800|||||||” header_font_size=”45px” header_line_height=”1.3em” body_font=”|800|||||||” body_text_color=”#000000″ body_font_size=”20px” body_line_height=”1.6em” use_background_color=”off” custom_button=”on” button_text_size=”14px” button_text_color=”#ffffff” button_bg_color=”#00a88d” button_border_width=”8px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”60px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” background_layout=”light” animation_direction=”bottom” header_font_size_tablet=”” header_font_size_phone=”30px” header_font_size_last_edited=”on|phone” button_text_color_hover=”#ffffff” button_border_radius_hover=”66px” button_letter_spacing_hover=”1px” button_bg_color_hover=”rgba(47,56,84,0.9)” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”on” button_text_color__hover=”#ffffff” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”on” button_border_radius__hover=”66px” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”on” button_letter_spacing__hover=”1px” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”rgba(47,56,84,0.9)” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Products” _builder_version=”4.5.1″ background_color=”#f3f3f1″ custom_padding=”20px||11px||false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.5.1″ custom_padding=”8px||17px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.1″ text_font=”|500|||||||” text_text_color=”#000000″ quote_font=”||||||||” header_font=”||||||||” header_2_font=”|800|||||||” header_2_font_size=”40px” header_2_line_height=”1.4em” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||12px|||” global_colors_info=”{}”]<\/p>\n

A capacidade do recetor GPR55,<\/strong>que \u00e9 hoje considerado o terceiro recetor canabin\u00f3ide identificado<\/a> <\/strong> no sistema endocanabin\u00f3ide humano, foi ilustrada num estudo cient\u00edfico de 2018. Descobriu-se que este recetor desempenha um papel fundamental no tratamento da s\u00edndrome de Dravet, um tipo raro e grave de epilepsia.<\/p>\n

De acordo com o resumo publicado em Proceedings of the National Academy of Sciences,<\/a>um grupo de investigadores da Universidade de Washington em Seattle viu potencial para“estender o<\/strong>espectro da terapia do CBD” a atividades semelhantes ao autismo. Tal permitiria fornecer informa\u00e7\u00f5es mecan\u00edsticas iniciais sobre as a\u00e7\u00f5es terap\u00eauticas do CBD.<\/p>\n

Deve dizer-se que os recetores canabin\u00f3ides s\u00e3o mol\u00e9culas de prote\u00edna complexas, que interagem com os compostos ativos da can\u00e1bis no corpo humano, no que \u00e9 conhecido como o sistema endocanabin\u00f3ide.<\/a><\/p>\n

Os cientistas t\u00eam falado sobre recetores CB1 e CB2<\/a> <\/strong>desde os anos 90. No entanto, a investiga\u00e7\u00e3o sobre o recetor GPR55 e o papel que parece desempenhar no sistema endocanabin\u00f3ide como outro recetor canabin\u00f3ide especial est\u00e1 em fase inicial.<\/p>\n

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As origens do terceiro recetor canabin\u00f3ide GPR55<\/h2>\n

O recetor GPR55 <\/strong>foi identificado pela primeira vez como um “novo recetor canabin\u00f3ide” em 2007. Isto foi realizado e publicado pelo Centro Nacional de Informa\u00e7\u00e3o Biotecnol\u00f3gica (NCBI).<\/a> Anteriormente, era considerado um “recetor \u00f3rf\u00e3o”, o que significava que a sua fun\u00e7\u00e3o exata n\u00e3o tinha sido determinada.<\/strong><\/p>\n

Nos anos seguintes, acumularam-se provas de que o recetor GPR55 poderia ser respons\u00e1vel por muitos dos benef\u00edcios documentados dos utilizadores de can\u00e1bis.<\/p>\n

Por exemplo, o recetor GPR55 teve um papel importante no controlo da atividade osteoclasta. Ou seja, na forma\u00e7\u00e3o \u00f3ssea e na cura, que foi revelado num estudo de 2009 publicado no PNAS.<\/a> O Centro Nacional de Informa\u00e7\u00e3o Biotecnol\u00f3gica (NCBI) tamb\u00e9m publicou um relat\u00f3rio em 2016 afirmando que encontrou um papel semelhante na gest\u00e3o da inflama\u00e7\u00e3o.<\/p>\n

Al\u00e9m disso, uma pesquisa de 2015 sobre fronteiras na farmacologia descobriu<\/a>que dois recetores \u00f3rf\u00e3os, bem como o recetor GPR55, podem ser alvos terap\u00eauticos promissores. Isto significa que desempenhariam v\u00e1rias fun\u00e7\u00f5es fisiol\u00f3gicas, desde o al\u00edvio a dist\u00farbios gastrointestinais,<\/strong>at\u00e9 dist\u00farbios hep\u00e1ticos.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Features” _builder_version=”4.5.1″ background_color=”#f3f3f1″ custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” admin_label=”CTA Row” module_class=” et_pb_row_fullwidth” _builder_version=”4.8.2″ background_color=”#00a88d” width=”100%” width_tablet=”100%” width_phone=”” width_last_edited=”on|desktop” max_width=”100%” max_width_tablet=”100%” max_width_phone=”” max_width_last_edited=”on|desktop” custom_padding=”0px|0px|0px|0px” make_fullwidth=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.5.1″ background_enable_image=”off” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/receptor-cannabinoide-GPR55.jpg” alt=”Recetor canabin\u00f3ide GPR55″ title_text=”Recetor canabin\u00f3ide GPR55″ force_fullwidth=”on” _builder_version=”4.9.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.8.2″ background_enable_color=”off” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_cta title=”O que a ci\u00eancia diz sobre o recetor canabin\u00f3ide GPR55?” button_url=”#top” _builder_version=”4.14.5″ header_font=”|800|||||||” header_text_color=”#ffffff” header_font_size=”35px” body_font=”Montserrat|500|||||||” body_text_color=”#ffffff” body_link_text_color=”#000000″ use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#ffffff” button_bg_color=”#2f3854″ button_border_width=”10px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”60px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” button_alignment=”left” text_orientation=”left” max_width=”580px” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|desktop” module_alignment=”left” custom_margin=”|||” custom_padding=”40px|60px|2px|60px||” hover_enabled=”0″ header_font_size_tablet=”25px” header_font_size_phone=”20px” header_font_size_last_edited=”on|desktop” button_text_color_hover=”#2f3854″ button_border_radius_hover=”66px” button_letter_spacing_hover=”1px” button_bg_color_hover=”#ffffff” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”on” button_text_color__hover=”#2f3854″ button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”on” button_border_radius__hover=”66px” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”on” button_letter_spacing__hover=”1px” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#ffffff” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off” sticky_enabled=”0″]<\/p>\n

Hoje \u00e9 sabido que o recetor GPR55 est\u00e1 presente no c\u00e9rebro e no trato gastrointestinal.<\/a> <\/strong> \u00c9 nomeado porque \u00e9 o n\u00famero 55 em uma sequ\u00eancia de recetores acoplado \u00e0 prote\u00edna G, que tamb\u00e9m inclui recetores CB1 e CB2. G significa guanina,<\/strong>que \u00e9 uma base de nucle\u00f3tidos, e \u00e9, portanto, considerada um dos “blocos de constru\u00e7\u00e3o” do ADN.<\/p>\n

Devido \u00e0 forma como estes receptores canabinoides<\/a> interagem com as c\u00e9lulas, a guanina est\u00e1 associada a todas elas.<\/p>\n

De acordo com Robert Sindelar, que \u00e9 diretor cient\u00edfico e diretor de desenvolvimento de produtos na BAS Research, um produtor autorizado de produtos de can\u00e1bis, sediado em Berkeley, Calif\u00f3rnia, o recetor canabin\u00f3ide recebe o produto qu\u00edmico e depois envia sinais para c\u00e9lulas como neur\u00f3nios.<\/p>\n

Segundo Sindelar, durante muitos anos, a via endocanabin\u00f3ide tem sido uma esp\u00e9cie de caixa aparafusada, em grande parte devido \u00e0s restri\u00e7\u00f5es dos estudos federais.” Portanto, os cientistas est\u00e3o realmente come\u00e7ando a descobrir como estes recetores canabin\u00f3ides fazem o que fazem.<\/a><\/p>\n

[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.5.1″ _module_preset=”default” background_color=”#f3f3f1″ custom_padding=”14px||27px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.5.1″ _module_preset=”default” custom_padding=”12px||13px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” header_2_font=”|800|||||||” header_2_text_align=”center” header_2_font_size=”35px” header_2_line_height=”1.2em” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||-5px|||” custom_padding=”||0px|||” header_2_font_size_tablet=”25px” header_2_font_size_phone=”20px” header_2_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

At\u00e9 agora, o CBD tem um efeito positivo em pessoas com convuls\u00f5es.<\/strong> No entanto, at\u00e9 ao momento n\u00e3o se sabe ao certo o que leva a que isto aconte\u00e7a. Os cientistas est\u00e3o a recuperar o que a experi\u00eancia convencional e os dados aned\u00f3ticos lhes permitiram saber sobre o recetor GPR55.<\/p>\n

A sua rela\u00e7\u00e3o com a s\u00edndrome de Dravet<\/h2>\n

Sindelar refere-se \u00e0 s\u00edndrome de Dravet, no sentido de que \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica que foi anteriormente considerada incur\u00e1vel.<\/strong> No entanto, muitos pacientes descobriram que tomar CBD todos os dias \u00e9 a sua \u00fanica fonte de al\u00edvio.<\/p>\n

Os investigadores descobriram o mecanismo ou modo de a\u00e7\u00e3o atrav\u00e9s do qual o CBD envia uma mensagem para uma parte do c\u00e9rebro que informa uma crian\u00e7a com s\u00edndrome de Dravet se eles devem ou n\u00e3o ter uma convuls\u00e3o.<\/p>\n

Como h\u00e1 um n\u00famero crescente de evid\u00eancias em torno do recetor GPR55, incluindo um estudo de 2017 que encontrou o papel dos recetores no tratamento da s\u00edndrome de Dravet, os investigadores est\u00e3o sob mais press\u00e3o para continuar a pesquisar o recetor GPR55. Este \u00e9 um alvo potencial para o tratamento da epilepsia, especialmente em termos de como interage com o CBD.<\/strong><\/p>\n

E de acordo com Sindelar, tais investiga\u00e7\u00f5es teriam outras implica\u00e7\u00f5es. Ou seja, a investiga\u00e7\u00e3o est\u00e1 a revelar o mist\u00e9rio emp\u00edrico em torno do que as pessoas observam na realidade ou aned\u00f3ticamente.<\/p>\n

Isto pode fornecer o teste necess\u00e1rio para desprogramar estes produtos qu\u00edmicos. Em muitos aspetos, tudo isto acabaria por conduzir a uma mudan\u00e7a na forma como os governos classificam os canabin\u00f3ides. Se esta altera\u00e7\u00e3o ocorresse, estas quest\u00f5es seriam autorizadas a ser estudadas mais aprofundadamente. At\u00e9 a investiga\u00e7\u00e3o sobre os canabin\u00f3ides seria eleg\u00edvel para financiamento federal.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.5.1″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”40px||40px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.4.4″ locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.4.4″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cbd-aceite-comprar.jpg” alt=”efic\u00e1cia do cbd” title_text=”Efici\u00eancia do CBD” _builder_version=”4.9.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.4.4″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ header_2_font=”|800|||||||” header_2_text_color=”#000000″ header_2_font_size=”35px” header_2_line_height=”1.2em” custom_margin=”||||false|false” custom_margin_tablet=”|||0%|false|false” custom_margin_last_edited=”off|desktop” header_2_font_size_tablet=”25px” header_2_font_size_phone=”20px” header_2_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

GPR55 pode ser a chave para a efic\u00e1cia do CBD<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n

O CBD aumentou em popularidade e aceita\u00e7\u00e3o nos \u00faltimos anos como um canabin\u00f3ide n\u00e3o-psicoactivo. Al\u00e9m disso, \u00e9 sabido que tem uma grande variedade de aplica\u00e7\u00f5es medicinais.<\/p>\n

As suas propriedades anti-tumorais, anticonvulsantes e anti-inflamat\u00f3rias foram investigadas, com resultados promissores. Como o CBD n\u00e3o tem mostrado nenhuma afinidade para os recetores CB1 e CB2,<\/strong>acredita-se que funcione atrav\u00e9s de outras vias. Tudo sugere que o canabin\u00f3ide \u00e9 atra\u00eddo pelos recetores vainilloides e pelo recetor 5-HT1A.<\/p>\n

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[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.5.1″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”21px||18px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.5.1″ custom_margin=”|auto|-2px|auto||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.5.1″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cual-es-el-mejor-aceite-de-cbd.jpg” alt=”thc cbd neurog\u00e9nese” title_text=”Neurog\u00e9nese THC CBD” align=”center” _builder_version=”4.5.1″ background_enable_image=”off” background_size=”contain” max_width_phone=”300px” max_width_last_edited=”off|tablet” custom_margin=”|||-30%|false|false” custom_margin_tablet=”|||-15%|false|false” custom_margin_phone=”|||-10%|false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.4.4″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n

Outros canabin\u00f3ides tamb\u00e9m foram demonstrados para se juntar ao recetor GPR55, mas nestes casos o CBD inibe a sua fun\u00e7\u00e3o. Isto pode explicar alguns dos seus benef\u00edcios medicinais.<\/p>\n

Al\u00e9m disso, acredita-se que o GPR55 desempenha um papel importante no cancro durante a investiga\u00e7\u00e3o in vitro precoce. O potencial invasivo das c\u00e9lulas metast\u00e1ticas, bem como o desenvolvimento de met\u00e1stases \u00f3sseas em v\u00e1rios tipos de tumores est\u00e3o relacionados com a sinaliza\u00e7\u00e3o GPR55.<\/p>\n

A sinaliza\u00e7\u00e3o GPR55 tamb\u00e9m tem sido associada \u00e0 progress\u00e3o do cancro, particularmente no que diz respeito a doen\u00e7as linfaloneras.<\/p>\n

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Itens relacionados<\/h4>\n

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Inscreva-se e receba um desconto de 10% na sua compra. <\/p>\n

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5% CDB<\/a><\/p>\n

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20% CDB<\/a><\/p>\n

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B\u00e1lsamo de Cura<\/a><\/p>\n

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Crema dolor muscular<\/a><\/p>\n

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Creme de m\u00e3os<\/a><\/p>\n

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Creme noturno<\/a><\/p>\n

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icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”CBD por grosso” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjUyMDEifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Sexta-feira Negra” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjEyODY0In19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.5.1″ background_color=”#00205c” custom_padding=”4%|5%|4%|4%|true|false” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”off|desktop” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#96bf00″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700||on|||||” header_4_text_color=”#ffffff” header_4_font_size=”14px” header_4_letter_spacing=”2px” header_4_line_height=”1.8em” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Guias<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-07-2.png” alt=”s\u00edmbolo do higea” title_text=”spice-shop-07″ _builder_version=”4.5.1″ custom_margin_tablet=”0px||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb title=”Combate \u00e0 ansiedade” url=”https:\/\/higeacbd.com\/pt-pt\/combate-a-ansiedade” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Como tomar \u00f3leo de CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjUzMiJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”O que \u00e9 a CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjU4NyJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Benef\u00edcios da CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjY1OSJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”CBD e CBDA” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE5NjgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Melhor CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIxNDgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Estudos cient\u00edficos” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Antidepressivos” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM3MTQxIn19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.5.1″ background_color=”#00a88d” custom_padding=”4%|5%|4%|4%|true|false” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”off|desktop” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#96bf00″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700||on|||||” header_4_text_color=”#ffffff” header_4_font_size=”14px” header_4_letter_spacing=”2px” header_4_line_height=”1.8em” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Saiba mais<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-07-2.png” alt=”s\u00edmbolo do higea” title_text=”spice-shop-07″ _builder_version=”4.5.1″ custom_margin_tablet=”0px||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb title=”Blog” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6Ijc3NyJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Animais de estima\u00e7\u00e3o da CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE4OTgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Citoquinas” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE5OTkifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Terpenos” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI3NDEifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Extrac\u00e7\u00e3o da CDB” url=”https:\/\/higeacbd.com\/pt-pt\/oleos\/metodos-de-extracao-cbd” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”\u00d3leos veiculares” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIzNzcifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”O que s\u00e3o flavon\u00f3ides” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIyOTMifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.4.9″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.4.4″ background_color=”#ffffff” custom_padding=”80px|60px|80px|60px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#000000″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700|||||||” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Aviso legal e pol\u00edtica de privacidade<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-32-1-1.png” alt=”s\u00edmbolo do higea” title_text=”s\u00edmbolo do higea” _builder_version=”4.5.1″ locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

AVISO LEGAL<\/a><\/p>\n

[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]PRIVACIDADE E COOKIES<\/a>[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

POL\u00cdTICA DE DEVOLU\u00c7\u00c3O<\/a><\/p>\n

[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]contato<\/a>[\/et_pb_blurb][et_pb_text _builder_version=”4.6.5″ _module_preset=”default” text_font_size=”15px” global_colors_info=”{}”]pedidos@higeacbd.com<\/a>[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/08\/formas-de-pago.png” alt=”op\u00e7\u00f5es de pagamento” title_text=”op\u00e7\u00f5es de pagamento” _builder_version=”4.6.5″ _module_preset=”default” custom_margin=”10px||10px||false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”DMCA protected” _builder_version=”4.6.5″ _module_preset=”default” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”] \"DMCA.com<\/a><\/p>\n