{"id":36210,"date":"2021-03-08T18:28:46","date_gmt":"2021-03-08T18:28:46","guid":{"rendered":"https:\/\/higeacbd.com\/huiles\/gpr55-un-troisieme-recepteur-cannabinoide\/"},"modified":"2025-03-24T12:05:39","modified_gmt":"2025-03-24T12:05:39","slug":"gpr55-un-troisieme-recepteur-cannabinoide","status":"publish","type":"post","link":"https:\/\/higeacbd.com\/fr\/datos\/gpr55-un-troisieme-recepteur-cannabinoide","title":{"rendered":"GPR55 : Un troisi\u00e8me r\u00e9cepteur cannabino\u00efde ?"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Hero” _builder_version=”4.9.1″ background_color=”rgba(255,255,255,0.65)” background_image=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/gpr55.jpg” background_blend=”soft-light” custom_padding=”3vw||1vw|||” global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_cta title=”GPR55 : Un troisi\u00e8me r\u00e9cepteur cannabino\u00efde ?” _builder_version=”4.9.0″ header_level=”h1″ header_font=”|800|||||||” header_font_size=”45px” header_line_height=”1.3em” body_font=”|800|||||||” body_text_color=”#000000″ body_font_size=”20px” body_line_height=”1.6em” use_background_color=”off” custom_button=”on” button_text_size=”14px” button_text_color=”#ffffff” button_bg_color=”#00a88d” button_border_width=”8px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”60px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” background_layout=”light” animation_direction=”bottom” header_font_size_tablet=”” header_font_size_phone=”30px” header_font_size_last_edited=”on|phone” button_text_color_hover=”#ffffff” button_border_radius_hover=”66px” button_letter_spacing_hover=”1px” button_bg_color_hover=”rgba(47,56,84,0.9)” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”on” button_text_color__hover=”#ffffff” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”on” button_border_radius__hover=”66px” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”on” button_letter_spacing__hover=”1px” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”rgba(47,56,84,0.9)” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Products” _builder_version=”4.5.1″ background_color=”#f3f3f1″ custom_padding=”20px||11px||false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.5.1″ custom_padding=”8px||17px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.1″ text_font=”|500|||||||” text_text_color=”#000000″ quote_font=”||||||||” header_font=”||||||||” header_2_font=”|800|||||||” header_2_font_size=”40px” header_2_line_height=”1.4em” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||12px|||” global_colors_info=”{}”]<\/p>\n

La capacit\u00e9 du r\u00e9cepteur GPR55<\/strong>, d\u00e9sormais consid\u00e9r\u00e9 comme le troisi\u00e8me r\u00e9cepteur cannabino\u00efde<\/a><\/strong> identifi\u00e9 dans le syst\u00e8me endocannabino\u00efde humain, a \u00e9t\u00e9 illustr\u00e9e dans une \u00e9tude scientifique de 2018. On a d\u00e9couvert que ce r\u00e9cepteur jouait un r\u00f4le cl\u00e9 dans le traitement du syndrome de Dravet, une forme rare et grave d’\u00e9pilepsie.<\/p>\n

Selon le r\u00e9sum\u00e9 publi\u00e9 dans les Actes de l’Acad\u00e9mie nationale des sciences<\/a>, un groupe de chercheurs de l’Universit\u00e9 de Washington \u00e0 Seattle a vu la possibilit\u00e9 d‘”\u00e9tendre le spectre de la th\u00e9rapie CBD<\/strong>” aux activit\u00e9s de type autiste. Il serait donc possible de fournir des informations m\u00e9canistes initiales sur les actions th\u00e9rapeutiques de la CDB.<\/p>\n

Il faut dire que les r\u00e9cepteurs cannabino\u00efdes sont des mol\u00e9cules prot\u00e9iques complexes, qui interagissent avec les compos\u00e9s actifs du cannabis dans le corps humain, dans ce que l’on appelle le syst\u00e8me endocannabino\u00efde<\/a>.<\/p>\n

Les scientifiques ont parl\u00e9 de R\u00e9cepteurs CB1 et CB2<\/a> <\/strong>depuis les ann\u00e9es 1990. Cependant, les recherches sur le r\u00e9cepteur GPR55 et le r\u00f4le qu’il semble jouer dans le syst\u00e8me endocannabino\u00efde en tant qu’autre r\u00e9cepteur cannabino\u00efde sp\u00e9cial n’en sont qu’\u00e0 leurs d\u00e9buts.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=”Produits” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” global_module=”16824″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ _module_preset=”default” background_enable_color=”off” global_colors_info=”{}”][et_pb_shop type=”best_selling” posts_number=”8″ show_pagination=”on” module_class=”custom-shop” _builder_version=”4.13.0″ _module_preset=”default” title_font=”|700|||||||” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][\/et_pb_shop][et_pb_signup mailchimp_list=”higeacbd|5b4d14cf0e” first_name_field=”off” last_name_field=”off” title=”Abonnez-vous et b\u00e9n\u00e9ficiez d\u2019une r\u00e9duction de 10%” disabled_on=”off|off|off” _builder_version=”4.13.0″ header_level=”h4″ header_font=”|800|||||||” header_text_align=”center” header_text_color=”#000000″ header_font_size=”35px” header_line_height=”1.2em” use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#00a88d” button_bg_color=”rgba(0,0,0,0)” button_border_width=”0px” button_border_radius=”0px” button_letter_spacing=”2px” button_font=”|700||on|||||” button_use_icon=”off” button_custom_padding=”18px|0px|18px|0px|true|true” button_custom_padding_tablet=”14px||14px||true|true” button_custom_padding_phone=”12px||12px||true|true” button_custom_padding_last_edited=”on|phone” background_layout=”light” header_font_size_tablet=”25px” header_font_size_phone=”20px” header_font_size_last_edited=”on|desktop” button_text_size_tablet=”14px” button_text_size_phone=”12px” button_text_size_last_edited=”on|phone” box_shadow_style_button=”preset4″ box_shadow_horizontal_button=”0px” box_shadow_vertical_button=”2px” box_shadow_color_button=”#00a88d” global_colors_info=”{}” button_text_color__hover=”#28221d” button_text_color__hover_enabled=”on|hover” box_shadow_color_button__hover=”#000000″ box_shadow_color_button__hover_enabled=”on|desktop”][\/et_pb_signup][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.5.1″ _module_preset=”default” background_color=”#f3f3f1″ custom_padding=”14px||27px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.5.1″ _module_preset=”default” custom_padding=”12px||13px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” header_2_font=”|800|||||||” header_2_text_align=”center” header_2_font_size=”35px” header_2_line_height=”1.2em” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||-5px|||” custom_padding=”||0px|||” header_2_font_size_tablet=”25px” header_2_font_size_phone=”20px” header_2_font_size_last_edited=”on|tablet” global_colors_info=”{}”]<\/p>\n

Les origines du troisi\u00e8me r\u00e9cepteur cannabino\u00efde GPR55<\/h2>\n

Le r\u00e9cepteur GPR55 <\/strong>a \u00e9t\u00e9 identifi\u00e9 pour la premi\u00e8re fois comme un “nouveau r\u00e9cepteur cannabino\u00efde” en 2007. C’est ce qui ressort d’une \u00e9tude men\u00e9e et publi\u00e9e par le Centre national d’information sur les biotechnologies (NCBI)<\/a>. Il \u00e9tait auparavant consid\u00e9r\u00e9 comme un “r\u00e9cepteur orphelin”, ce qui signifie que sa fonction exacte n’avait pas \u00e9t\u00e9 d\u00e9termin\u00e9e<\/strong>.<\/p>\n

Au cours des ann\u00e9es qui ont suivi, les preuves se sont accumul\u00e9es que le r\u00e9cepteur GPR55 pourrait \u00eatre responsable de bon nombre des avantages document\u00e9s de la consommation de cannabis.<\/p>\n

Par exemple, on a d\u00e9couvert que le r\u00e9cepteur GPR55 joue un r\u00f4le important dans le contr\u00f4le de l’activit\u00e9 des ost\u00e9oclastes. C’est-\u00e0-dire dans la formation et la gu\u00e9rison des os, ce qui a \u00e9t\u00e9 r\u00e9v\u00e9l\u00e9 dans une \u00e9tude de 2009 publi\u00e9e dans PNAS<\/a>. Le Centre national d’information sur les biotechnologies (NCBI), a \u00e9galement publi\u00e9 un rapport en 2016 indiquant qu’il a trouv\u00e9 un r\u00f4le similaire dans la gestion de l’inflammation.<\/p>\n

De plus, une recherche men\u00e9e en 2015 dans Frontiers in Pharmacology<\/a> a r\u00e9v\u00e9l\u00e9 que deux r\u00e9cepteurs orphelins, ainsi que le r\u00e9cepteur GPR55, pourraient \u00eatre des cibles th\u00e9rapeutiques prometteuses. En effet, ils remplissent diverses fonctions physiologiques, qui vont du soulagement des troubles gastro-intestinaux<\/strong> aux troubles osseux.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Features” _builder_version=”4.5.1″ background_color=”#f3f3f1″ custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” admin_label=”Ligne CTA” module_class=” et_pb_row_fullwidth” _builder_version=”4.8.2″ background_color=”#00a88d” width=”100%” width_tablet=”100%” width_phone=”” width_last_edited=”on|desktop” max_width=”100%” max_width_tablet=”100%” max_width_phone=”” max_width_last_edited=”on|desktop” custom_padding=”0px|0px|0px|0px” make_fullwidth=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.5.1″ background_enable_image=”off” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/receptor-cannabinoide-GPR55.jpg” alt=”r\u00e9cepteur cannabino\u00efde GPR55″ title_text=”r\u00e9cepteur cannabino\u00efde GPR55″ force_fullwidth=”on” _builder_version=”4.9.1″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.8.2″ background_enable_color=”off” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_cta title=”Que dit la science \u00e0 propos du r\u00e9cepteur cannabino\u00efde GPR55 ?” button_url=”#top” _builder_version=”4.14.5″ header_font=”|800|||||||” header_text_color=”#ffffff” header_font_size=”35px” body_font=”Montserrat|500|||||||” body_text_color=”#ffffff” body_link_text_color=”#000000″ use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#ffffff” button_bg_color=”#2f3854″ button_border_width=”10px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”60px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” button_alignment=”left” text_orientation=”left” max_width=”580px” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|desktop” module_alignment=”left” custom_margin=”|||” custom_padding=”40px|60px|2px|60px||” hover_enabled=”0″ header_font_size_tablet=”25px” header_font_size_phone=”20px” header_font_size_last_edited=”on|desktop” button_text_color_hover=”#2f3854″ button_border_radius_hover=”66px” button_letter_spacing_hover=”1px” button_bg_color_hover=”#ffffff” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”on” button_text_color__hover=”#2f3854″ button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”on” button_border_radius__hover=”66px” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”on” button_letter_spacing__hover=”1px” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#ffffff” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off” sticky_enabled=”0″]<\/p>\n

On sait maintenant que le r\u00e9cepteur GPR55 est pr\u00e9sent dans le cerveau et le tractus gastro-intestinal<\/a><\/strong>. Il est ainsi nomm\u00e9 parce qu’il est le num\u00e9ro 55 dans une s\u00e9quence de r\u00e9cepteurs coupl\u00e9s aux prot\u00e9ines G, qui comprend \u00e9galement les r\u00e9cepteurs CB1 et CB2. Le G repr\u00e9sente la guanine<\/strong>, qui est une base nucl\u00e9otidique, et est donc consid\u00e9r\u00e9 comme l’un des “\u00e9l\u00e9ments constitutifs” de l’ADN.<\/p>\n

En raison de la mani\u00e8re dont ces r\u00e9cepteurs cannabino\u00efdes<\/a> interagissent avec les cellules, la guanine est associ\u00e9e \u00e0 chacun d’entre eux.<\/p>\n

Selon Robert Sindelar, directeur scientifique et directeur du d\u00e9veloppement des produits chez BAS Research, un producteur de cannabis sous licence bas\u00e9 \u00e0 Berkeley, en Californie, le r\u00e9cepteur cannabino\u00efde re\u00e7oit le produit chimique et envoie ensuite des signaux \u00e0 des cellules telles que les neurones.<\/p>\n

Selon Sindelar, pendant de nombreuses ann\u00e9es, la voie des endocannabino\u00efdes a \u00e9t\u00e9 une sorte de bo\u00eete ferm\u00e9e, en grande partie \u00e0 cause des restrictions sur les \u00e9tudes f\u00e9d\u00e9rales. Les scientifiques commencent<\/a> donc \u00e0 d\u00e9couvrir comment ces r\u00e9cepteurs cannabino\u00efdes agissent<\/a>.<\/p>\n

[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.5.1″ _module_preset=”default” background_color=”#f3f3f1″ custom_padding=”14px||27px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.5.1″ _module_preset=”default” custom_padding=”12px||13px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.5.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” header_2_font=”|800|||||||” header_2_text_align=”center” header_2_font_size=”35px” header_2_line_height=”1.2em” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||-5px|||” custom_padding=”||0px|||” header_2_font_size_tablet=”25px” header_2_font_size_phone=”20px” header_2_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

Jusqu’\u00e0 pr\u00e9sent, on sait que le CBD a un effet positif sur les personnes souffrant de crises d’\u00e9pilepsie<\/strong>. Toutefois, on ne sait pas encore avec certitude ce qui en est la cause. Les scientifiques rattrapent le retard qu’ils ont pris sur l’exp\u00e9rience conventionnelle et les donn\u00e9es anecdotiques qui leur ont permis de d\u00e9couvrir le r\u00e9cepteur GPR55.<\/p>\n

Sa relation avec le syndrome de Dravet<\/h2>\n

Sindelar fait r\u00e9f\u00e9rence au syndrome de Dravet, en ce sens qu’il s’agit d’une maladie g\u00e9n\u00e9tique qui \u00e9tait auparavant consid\u00e9r\u00e9e comme incurable<\/strong>. Cependant, de nombreux patients ont d\u00e9couvert que la prise quotidienne de CBD est leur seule source de soulagement.<\/p>\n

Les chercheurs ont d\u00e9couvert le m\u00e9canisme ou le mode d’action par lequel la CDB envoie un message \u00e0 une partie du cerveau qui informe un enfant atteint du syndrome de Dravet de faire ou non une crise.<\/p>\n

Comme il existe un ensemble croissant de preuves entourant le r\u00e9cepteur GPR55, y compris une \u00e9tude de 2017 qui a d\u00e9couvert le r\u00f4le des r\u00e9cepteurs dans le traitement du syndrome de Dravet, les chercheurs sont soumis \u00e0 une pression accrue pour continuer \u00e0 \u00e9tudier le r\u00e9cepteur GPR55. Ce qui pr\u00e9c\u00e8de est une cible potentielle pour le traitement de l’\u00e9pilepsie, notamment en ce qui concerne son interaction avec la CDB<\/strong>.<\/p>\n

Et selon Sindelar, de telles enqu\u00eates auraient d’autres implications. En d’autres termes, la recherche r\u00e9v\u00e8le le myst\u00e8re empirique entourant ce que les gens observent dans la r\u00e9alit\u00e9 ou de mani\u00e8re anecdotique.<\/p>\n

Cela peut fournir la preuve n\u00e9cessaire pour d\u00e9programmer ces produits chimiques. \u00c0 bien des \u00e9gards, tout cela conduirait finalement \u00e0 un changement dans la mani\u00e8re dont les gouvernements classifient les cannabino\u00efdes. Un tel changement permettrait d’approfondir ces questions. M\u00eame la recherche sur les cannabino\u00efdes serait \u00e9ligible au financement f\u00e9d\u00e9ral.<\/p>\n

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Le GPR55 pourrait \u00eatre la cl\u00e9 de l’efficacit\u00e9 de la CDB<\/h2>\n

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La CBD a gagn\u00e9 en popularit\u00e9 et en acceptation ces derni\u00e8res ann\u00e9es en tant que cannabino\u00efde non psychoactif. En outre, il est connu pour avoir une grande vari\u00e9t\u00e9 d’applications m\u00e9dicales.<\/p>\n

Ses propri\u00e9t\u00e9s antitumorales, anticonvulsives et anti-inflammatoires ont \u00e9t\u00e9 \u00e9tudi\u00e9es avec des r\u00e9sultats prometteurs. Comme la CBD n’a pas montr\u00e9 d’affinit\u00e9 pour les r\u00e9cepteurs CB1 et CB2<\/strong>, on pense qu’elle fonctionne par d’autres voies. Tout porte \u00e0 croire que le cannabino\u00efde est attir\u00e9 par les r\u00e9cepteurs vanillo\u00efdes et le r\u00e9cepteur 5-HT1A.<\/p>\n

 <\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.5.1″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”21px||18px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.5.1″ custom_margin=”|auto|-2px|auto||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.5.1″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cual-es-el-mejor-aceite-de-cbd.jpg” alt=”neurogen\u00e8se de cbd de thc” title_text=”Neurogen\u00e8se du THC CBD” align=”center” _builder_version=”4.5.1″ background_enable_image=”off” background_size=”contain” max_width_phone=”300px” max_width_last_edited=”off|tablet” custom_margin=”|||-30%|false|false” custom_margin_tablet=”|||-15%|false|false” custom_margin_phone=”|||-10%|false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.4.4″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.9.0″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n

Il a \u00e9galement \u00e9t\u00e9 d\u00e9montr\u00e9 que d’autres cannabino\u00efdes se lient au r\u00e9cepteur GPR55, mais dans ces cas, la CDB inhibe sa fonction. Cela peut expliquer certains de ses bienfaits m\u00e9dicinaux.<\/p>\n

En outre, on pense que le GPR55 joue un r\u00f4le important dans le cancer au cours de la recherche in vitro pr\u00e9coce. Le potentiel invasif des cellules m\u00e9tastatiques ainsi que le d\u00e9veloppement de m\u00e9tastases osseuses dans divers types de tumeurs sont li\u00e9s par la signalisation GPR55.<\/p>\n

La signalisation GPR55 a \u00e9galement \u00e9t\u00e9 li\u00e9e \u00e0 la progression du cancer, en particulier dans les maladies lymphoprolif\u00e9ratives.<\/p>\n

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Articles connexes<\/h4>\n

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Abonnez-vous et b\u00e9n\u00e9ficiez d\u2019une r\u00e9duction de 10% sur votre achat. <\/p>\n

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boutique<\/h4>\n

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CBD \u00e0 5%<\/a><\/p>\n

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CBD \u00e0 20%<\/a><\/p>\n

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Baume cicatrisant<\/a><\/p>\n

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Crema dolor muscular<\/a><\/p>\n

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Cr\u00e8me pour les mains<\/a><\/p>\n

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Cr\u00e8me de nuit<\/a><\/p>\n

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global_colors_info=”{}” button_text_color__hover_enabled=”on|hover” button_text_color__hover=”#ffffff” box_shadow_color__hover_enabled=”off|hover” box_shadow_color__hover=”#e14a00″][\/et_pb_button][et_pb_blurb title=”Mon compte” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE0In19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Plan de convivialit\u00e9” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE1NjE0In19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Vente en gros CBD” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjUyMDEifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Vendredi noir” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjEyODY0In19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.5.1″ background_color=”#00205c” custom_padding=”4%|5%|4%|4%|true|false” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”off|desktop” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#96bf00″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700||on|||||” header_4_text_color=”#ffffff” header_4_font_size=”14px” header_4_letter_spacing=”2px” header_4_line_height=”1.8em” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Guides<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-07-2.png” alt=”simboolo higea” title_text=”spice-shop-07″ _builder_version=”4.5.1″ custom_margin_tablet=”0px||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb title=”Combattre l'anxi\u00e9t\u00e9” url=”https:\/\/higeacbd.com\/fr\/combattre-lanxiete” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Comment prendre de l\u2019huile de CBD” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjUzMiJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Qu\u2019est-ce que la CDB” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjU4NyJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Avantages cbd” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjY1OSJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”CBD et CBDA” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE5NjgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Meilleur CBD” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIxNDgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”\u00c9tudes scientifiques” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI1MTgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Antid\u00e9presseurs” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjM3MTQxIn19@” use_icon=”on” font_icon=”V||divi||400″ icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.5.1″ background_color=”#00a88d” custom_padding=”4%|5%|4%|4%|true|false” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”off|desktop” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#96bf00″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700||on|||||” header_4_text_color=”#ffffff” header_4_font_size=”14px” header_4_letter_spacing=”2px” header_4_line_height=”1.8em” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

En savoir plus<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-07-2.png” alt=”simboolo higea” title_text=”spice-shop-07″ _builder_version=”4.5.1″ custom_margin_tablet=”0px||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb title=”Blog” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6Ijc3NyJ9fQ==@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Animaux de compagnie CBD” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE4OTgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Cytokines” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE5OTkifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Terp\u00e8nes” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjI3NDEifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Extraction de CBD” url=”https:\/\/higeacbd.com\/fr\/huiles\/methodes-dextraction-de-cbd” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Huiles porteuses” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIzNzcifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Qu\u2019est-ce que les flavono\u00efdes” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIyOTMifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.13.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.4.9″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.4.4″ background_color=”#ffffff” custom_padding=”80px|60px|80px|60px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.5.1″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#000000″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700|||||||” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Avis juridique et politique de confidentialit\u00e9<\/h4>\n

[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-32-1-1.png” alt=”simboolo higea” title_text=”simboolo higea” _builder_version=”4.5.1″ locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

AVIS JURIDIQUE<\/a><\/p>\n

[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]CONFIDENTIALIT\u00c9 ET COOKIES<\/a>[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n

POLITIQUE DE RETOUR<\/a><\/p>\n

[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.13.0″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]CONTACT<\/a>[\/et_pb_blurb][et_pb_text _builder_version=”4.6.5″ _module_preset=”default” text_font_size=”15px” global_colors_info=”{}”]pedidos@higeacbd.com<\/a>[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/08\/formas-de-pago.png” alt=”m\u00e9thodes de paiement” title_text=”m\u00e9thodes de paiement” _builder_version=”4.6.5″ _module_preset=”default” custom_margin=”10px||10px||false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”DMCA protected” _builder_version=”4.6.5″ _module_preset=”default” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”] \"DMCA.com<\/a><\/p>\n