[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Products” _builder_version=”4.16″ background_color=”#f3f3f1″ custom_padding=”20px||11px||false|false” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_padding=”8px||17px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.20.2″ text_font=”|500|||||||” text_text_color=”#000000″ quote_font=”||||||||” header_font=”||||||||” header_2_font=”|800|||||||” header_2_font_size=”40px” header_2_line_height=”1.4em” text_orientation=”center” max_width=”80%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” custom_margin=”||12px|||” global_colors_info=”{}”]<\/p>\n
Bien que les personnes souffrant de d\u00e9pression prennent des antid\u00e9presseurs depuis des d\u00e9cennies, la science n’avait pas vraiment compris comment ils agissent sur le plan biologique – jusqu’\u00e0 pr\u00e9sent. Une nouvelle \u00e9tude sur le sujet remet en question tout ce que l’on savait jusqu’\u00e0 pr\u00e9sent sur le fonctionnement des antid\u00e9presseurs<\/strong>.<\/p>\n Cette nouvelle \u00e9tude sugg\u00e8re que les inhibiteurs s\u00e9lectifs de la recapture de la s\u00e9rotonine(ISRS), les m\u00e9dicaments \u00e0 action lente utilis\u00e9s dans le traitement de la d\u00e9pression, et la k\u00e9tamine \u00e0 action rapide se combinent directement avec un r\u00e9cepteur du facteur neurotrophique d\u00e9riv\u00e9 du cerveau(BDNF). Par cons\u00e9quent, ils favorisent la plasticit\u00e9 neuronale, qui \u00e0 son tour soulage la d\u00e9pression, mais sans utiliser la s\u00e9rotonine ou le glutamate.<\/p>\n Nous examinons ici les conclusions de cette nouvelle \u00e9tude sur le fonctionnement des antid\u00e9presseurs. Nous parlerons \u00e9galement un peu de l’utilisation du cannabidiol CBD et de ses propri\u00e9t\u00e9s antid\u00e9pressives<\/strong>.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=”Produits” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” global_module=”16824″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” background_enable_color=”off” global_colors_info=”{}”][et_pb_shop type=”best_selling” posts_number=”8″ show_pagination=”on” module_class=”custom-shop” _builder_version=”4.16″ _module_preset=”default” title_font=”|700|||||||” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][\/et_pb_shop][et_pb_signup mailchimp_list=”higeacbd|5b4d14cf0e” first_name_field=”off” last_name_field=”off” title=”Abonnez-vous et b\u00e9n\u00e9ficiez d\u2019une r\u00e9duction de 10%” disabled_on=”off|off|off” _builder_version=”4.16″ header_level=”h4″ header_font=”|800|||||||” header_text_align=”center” header_text_color=”#000000″ header_font_size=”35px” header_line_height=”1.2em” use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#00a88d” button_bg_color=”rgba(0,0,0,0)” button_border_width=”0px” button_border_radius=”0px” button_letter_spacing=”2px” button_font=”|700||on|||||” button_use_icon=”off” button_custom_padding=”18px|0px|18px|0px|true|true” button_custom_padding_tablet=”14px||14px||true|true” button_custom_padding_phone=”12px||12px||true|true” button_custom_padding_last_edited=”on|phone” background_layout=”light” header_font_size_tablet=”25px” header_font_size_phone=”20px” header_font_size_last_edited=”on|desktop” button_text_size_tablet=”14px” button_text_size_phone=”12px” button_text_size_last_edited=”on|phone” box_shadow_style_button=”preset4″ box_shadow_horizontal_button=”0px” box_shadow_vertical_button=”2px” box_shadow_color_button=”#00a88d” global_colors_info=”{}” button_text_color__hover=”#28221d” button_text_color__hover_enabled=”on|hover” box_shadow_color_button__hover=”#000000″ box_shadow_color_button__hover_enabled=”on|desktop”][\/et_pb_signup][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”28px|40px|18px|40px||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.20.4″ link_text_color=”#000000″ header_2_font=”|800|||||||” header_2_text_align=”center” header_2_text_color=”#ffffff” header_2_font_size=”40px” header_2_line_height=”1.2em” z_index=”2″ background_layout=”dark” max_width=”70%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” hover_enabled=”0″ header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|desktop” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n La recherche dont nous parlons est une \u00e9tude internationale <\/a>publi\u00e9e dans la revue Cell<\/a>, dirig\u00e9e par deux neuroscientifiques nomm\u00e9s Eero Castr\u00e9n<\/strong> et Plino Cassaroto<\/strong>. Elle a \u00e9t\u00e9 r\u00e9alis\u00e9e au Centre des neurosciences de l’Universit\u00e9 d’Helsinki en collaboration avec le d\u00e9partement de physique.<\/p>\n Le but de la recherche \u00e9tait de d\u00e9terminer comment les antid\u00e9presseurs interagissent avec un r\u00e9cepteur du BDNF appel\u00e9 TrkB<\/strong>. Plus pr\u00e9cis\u00e9ment, les m\u00e9dicaments suivants ont \u00e9t\u00e9 \u00e9tudi\u00e9s :<\/p>\n Au d\u00e9part, on pensait que les effets des ISRS, et ceux des antid\u00e9presseurs tricycliques<\/strong>, provenaient de leur propre capacit\u00e9 \u00e0 retenir davantage de s\u00e9rotonine et de noradr\u00e9naline dans le cerveau en augmentant leur taux dans la fente synaptique. De m\u00eame, on pensait que l’effet antid\u00e9presseur de la k\u00e9tamine visait \u00e0 inhiber les r\u00e9cepteurs du glutamate.<\/p>\n Ces trois antid\u00e9presseurs<\/strong> test\u00e9s dans le cadre de la recherche se sont av\u00e9r\u00e9s interagir avec le r\u00e9cepteur TrkB<\/strong>. Cependant, ils l’ont fait sans augmenter ou inhiber d’autres neurotransmetteurs tels que la s\u00e9rotonine, la nor\u00e9pin\u00e9phrine ou le glutamate.<\/p>\n Il convient de mentionner que d’autres recherches ont d\u00e9j\u00e0 identifi\u00e9 la relation entre les antid\u00e9presseurs et l’augmentation des facteurs neurotrophiques. C’est le cas du BDNF (brain-derived neurotrophic factor), qui joue un r\u00f4le crucial dans la r\u00e9gulation de la neuroplasticit\u00e9<\/strong>.<\/p>\n Cependant, les chercheurs pensaient que les antid\u00e9presseurs agissaient indirectement sur le BDNF via les r\u00e9cepteurs du glutamate et de la s\u00e9rotonine. Les r\u00e9sultats de cette recherche pourraient \u00eatre r\u00e9volutionnaires, car ils r\u00e9v\u00e8lent que les antid\u00e9presseurs se lient en fait directement aux r\u00e9cepteurs du BDNF<\/strong>.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.16″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”40px||40px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.16″ custom_padding=”||18px|||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/como-funcionan-los-antidepresivos.jpg” alt=”comment fonctionnent les antid\u00e9presseurs” title_text=”comment fonctionnent les antid\u00e9presseurs” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ header_2_font=”|800|||||||” header_2_text_color=”#000000″ header_2_font_size=”40px” header_2_line_height=”1.2em” custom_margin=”||||false|false” custom_margin_tablet=”|||0%|false|false” custom_margin_last_edited=”off|desktop” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.19.4″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n Depuis deux d\u00e9cennies, les scientifiques savent que les m\u00e9dicaments antid\u00e9presseurs et l’exercice a\u00e9robie favorisent la plasticit\u00e9 neuronale et la croissance de nouveaux neurones. Il existe \u00e9galement des recherches sur l’exercice et les troubles d\u00e9pressifs<\/a>, o\u00f9 la corr\u00e9lation entre l’augmentation du BDNF induite par l’exercice et un risque plus faible de trouble d\u00e9pressif majeur<\/strong> a \u00e9t\u00e9 \u00e9tudi\u00e9e.<\/p>\n En outre, d’autres recherches ont cherch\u00e9 \u00e0 d\u00e9terminer comment l’efficacit\u00e9 des antid\u00e9presseurs peut \u00eatre li\u00e9e au BDNF. Les chercheurs ont \u00e9galement d\u00e9termin\u00e9 comment une voie mol\u00e9culaire li\u00e9e \u00e0 la prot\u00e9ine activatrice 1 facilite une r\u00e9action en cha\u00eene qui active de multiples g\u00e8nes, lesquels favorisent \u00e0 leur tour la plasticit\u00e9 neuronale.<\/p>\n Cela permet au cerveau d’inverser les dommages neurologiques g\u00e9n\u00e9ralement associ\u00e9s \u00e0 la d\u00e9pression. Ce qui est int\u00e9ressant, c’est qu’au bout de deux ou trois semaines, les effets r\u00e9g\u00e9n\u00e9rateurs de ces changements peuvent \u00eatre vus et ressentis<\/strong>. Des \u00e9tudes ont permis d’expliquer pourquoi les ISRS prennent jusqu’\u00e0 14 jours pour \u00eatre actifs.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”46px|40px|41px|40px||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ link_text_color=”#000000″ header_2_font=”|800|||||||” header_2_text_align=”center” header_2_text_color=”#ffffff” header_2_font_size=”40px” header_2_line_height=”1.2em” z_index=”2″ background_layout=”dark” max_width=”70%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n Des recherches ant\u00e9rieures ont pu montrer que lors d’un traitement th\u00e9rapeutique avec des inhibiteurs s\u00e9lectifs de la recapture de la s\u00e9rotonine (ISRS), les antid\u00e9presseurs atteignent progressivement une concentration c\u00e9r\u00e9brale \u00e9lev\u00e9e pour se lier au r\u00e9cepteur TrkB<\/strong>. En revanche, la k\u00e9tamine et l’esketamine, administr\u00e9es par voie intraveineuse, atteignent le niveau requis pour lier Trkb en quelques minutes.<\/p>\n Selon les chercheurs, la diff\u00e9rence dans le d\u00e9but d’action des ISRS et de la k\u00e9tamine pourrait r\u00e9sulter de leur capacit\u00e9 diff\u00e9rente \u00e0 atteindre la concentration n\u00e9cessaire pour se lier au r\u00e9cepteur TrkB dans le cerveau. Il convient \u00e9galement de pr\u00e9ciser que la k\u00e9tamine \u00e9tait habituellement utilis\u00e9e comme anesth\u00e9sique, mais qu’elle est aujourd’hui de plus en plus utilis\u00e9e comme antid\u00e9presseur.<\/p>\n Bien que les ISRS se lient \u00e0 la prot\u00e9ine du transporteur de la s\u00e9rotonine beaucoup plus avidement qu’au TrkB, la k\u00e9tamine se lie au r\u00e9cepteur du glutamate et au TrkB \u00e0 des concentrations de m\u00e9dicament similaires.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.16″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”21px||18px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.16″ custom_margin=”|auto|-2px|auto||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/colesterol-y-antidepresivos.jpg” alt=”cholest\u00e9rol et antid\u00e9presseurs” title_text=”cholest\u00e9rol et antid\u00e9presseurs” align=”center” _builder_version=”4.16″ background_enable_image=”off” background_size=”contain” max_width_phone=”300px” max_width_last_edited=”off|tablet” custom_margin=”|||-30%|false|false” custom_margin_tablet=”|||-15%|false|false” custom_margin_phone=”|||-10%|false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ header_2_font=”|800|||||||” header_2_text_color=”#000000″ header_2_font_size=”40px” header_2_line_height=”1.2em” custom_margin=”||||false|false” custom_margin_tablet=”|||0%|false|false” custom_margin_last_edited=”off|desktop” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n L’emplacement pr\u00e9cis de la liaison des antid\u00e9presseurs dans la r\u00e9gion transmembranaire de TrkB a \u00e9t\u00e9 identifi\u00e9 par mod\u00e9lisation mol\u00e9culaire. Cette mod\u00e9lisation a \u00e9t\u00e9 r\u00e9alis\u00e9e par un groupe de chercheurs du d\u00e9partement de physique de l’universit\u00e9 d’Helsinki, dirig\u00e9 par le professeur Ilpo Vattuainen. Pour v\u00e9rifier le site, les scientifiques ont r\u00e9alis\u00e9 des \u00e9tudes de liaison biochimique et de mutations introduites dans le r\u00e9cepteur TrkB.<\/p>\n Un autre aspect pertinent d\u00e9montr\u00e9 par la mod\u00e9lisation mol\u00e9culaire est que la structure de TrkB est sensible \u00e0 la concentration de cholest\u00e9rol dans la membrane cellulaire<\/strong>. Ceci est important puisque TrkB se d\u00e9place dans des compartiments membranaires, connus pour \u00eatre une source riche en cholest\u00e9rol, tels que les membranes synaptiques. La liaison de TrkB au m\u00e9dicament antid\u00e9presseur stabilise les dim\u00e8res, qui sont des structures compos\u00e9es de deux r\u00e9cepteurs TrkB.<\/p>\n Lorsque cela se produit, le d\u00e9placement des r\u00e9cepteurs TrkB est inhib\u00e9, et dans le m\u00eame temps, leur quantit\u00e9 dans les membranes des cellules synaptiques est augment\u00e9e. Par cons\u00e9quent, les effets du BDNF sont renforc\u00e9s. En d’autres termes, les m\u00e9dicaments antid\u00e9presseurs n’activent pas directement le TrkB<\/strong>. Ce qu’ils font en fait, c’est sensibiliser le r\u00e9cepteur aux effets du BDNF.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”46px|40px|41px|40px||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ link_text_color=”#000000″ header_2_font=”|800|||||||” header_2_text_align=”center” header_2_text_color=”#ffffff” header_2_font_size=”40px” header_2_line_height=”1.2em” z_index=”2″ background_layout=”dark” max_width=”70%” max_width_tablet=”90%” max_width_phone=”100%” max_width_last_edited=”on|tablet” module_alignment=”center” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n Tout ce qui pr\u00e9c\u00e8de est important car il est prouv\u00e9 que les personnes suicidaires ou qui se sont suicid\u00e9es ont un faible taux de cholest\u00e9rol<\/strong>. Le probl\u00e8me est qu’il est compliqu\u00e9 d’\u00e9tablir une relation directe avec cette derni\u00e8re. D’autant plus que le cerveau utilise principalement le cholest\u00e9rol qu’il produit.<\/p>\n En outre, il pourrait y avoir un conflit avec les statines, qui sont des m\u00e9dicaments consomm\u00e9s par des millions de personnes dans le monde. Ces m\u00e9dicaments sont utilis\u00e9s pour contr\u00f4ler le taux de cholest\u00e9rol dans le sang. En fait, les chercheurs se sont demand\u00e9 si les statines ne bloquaient pas l’effet antid\u00e9presseur<\/strong>.<\/p>\n La recherche a \u00e9galement permis de montrer que lorsqu’on leur injectait une forte dose de statines, dans le but de r\u00e9duire le taux de cholest\u00e9rol dans le cerveau, les antid\u00e9presseurs n’augmentaient plus la neuroplasticit\u00e9. Les chercheurs ont ensuite analys\u00e9 des \u00e9tudes humaines dans lesquelles cela ne se produit pas parce que les statines n’atteignent pas le cerveau.<\/p>\n C’est-\u00e0-dire qu’avec les doses de statines normalement utilis\u00e9es chez l’homme, ces m\u00e9dicaments ne posent aucun probl\u00e8me. Quant au taux de cholest\u00e9rol sanguin, les scientifiques s’accordent \u00e0 dire que des recherches suppl\u00e9mentaires sont n\u00e9cessaires pour trouver un quelconque lien.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Features” _builder_version=”4.16″ background_color=”#f3f3f1″ custom_padding=”36px|0px|0px|0px||” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/cbd-antidepresivo.jpg” alt=”cbd antid\u00e9presseur” title_text=”cbd antid\u00e9presseur” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”||||||||” text_font_size=”16px” header_2_font=”|800|||||||” header_2_font_size=”40px” header_2_line_height=”1.2em” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n Maintenant que les chercheurs savent que la plasticit\u00e9 c\u00e9r\u00e9brale est fondamentale pour l’action des antid\u00e9presseurs, la question qui se pose est de savoir pourquoi certains antid\u00e9presseurs agissent plus rapidement que d’autres. Les scientifiques savent que de nombreux antid\u00e9presseurs classiques<\/strong>, tels que l’escitalopram ou la fluox\u00e9tine, mettent des semaines avant de commencer \u00e0 produire des effets visibles sur le plan psychologique.<\/p>\n En revanche, il existe d’autres antid\u00e9presseurs qui agissent beaucoup plus rapidement, comme la k\u00e9tamine, d\u00e9j\u00e0 mentionn\u00e9e. Tout semble indiquer qu’il s’agit d’un probl\u00e8me li\u00e9 au temps qu’il faut \u00e0 ces m\u00e9dicaments pour atteindre les concentrations n\u00e9cessaires dans le cerveau<\/strong>. Ce serait la raison pour laquelle cela prend plusieurs jours, et aussi pourquoi vous ne pouvez pas arr\u00eater d’en consommer.<\/p>\n Dans le cas des m\u00e9dicaments \u00e0 action rapide, ils peuvent \u00eatre en mesure de p\u00e9n\u00e9trer plus facilement la barri\u00e8re h\u00e9mato-enc\u00e9phalique, jusqu’\u00e0 ce qu’ils atteignent finalement la concentration n\u00e9cessaire pour activer le r\u00e9cepteur TrkB.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/investigacion-antidepresivos.jpg” alt=”recherche sur les antid\u00e9presseurs” title_text=”recherche sur les antid\u00e9presseurs” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”||||||||” text_font_size=”16px” header_2_font=”|800|||||||” header_2_font_size=”40px” header_2_line_height=”1.2em” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.16″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”21px||18px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.16″ custom_margin=”|auto|-2px|auto||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/antidepresivos-cbd-corto-plazo.jpg” alt=”antid\u00e9presseurs \u00e0 court terme \u00e0 base de cbd” title_text=”antid\u00e9presseurs \u00e0 court terme \u00e0 base de cbd” align=”center” _builder_version=”4.16″ background_enable_image=”off” background_size=”contain” max_width_phone=”300px” max_width_last_edited=”off|tablet” custom_margin=”|||-30%|false|false” custom_margin_tablet=”|||-15%|false|false” custom_margin_phone=”|||-10%|false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ header_2_font=”|800|||||||” header_2_text_color=”#000000″ header_2_font_size=”40px” header_2_line_height=”1.2em” custom_margin=”||||false|false” custom_margin_tablet=”|||0%|false|false” custom_margin_last_edited=”off|desktop” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n Les r\u00e9sultats ont r\u00e9v\u00e9l\u00e9 que le cannabidiol CBD induit un effet antid\u00e9presseur dose-d\u00e9pendant chez les souris. Ce m\u00eame test a \u00e9galement \u00e9t\u00e9 effectu\u00e9 sur des rats, et les r\u00e9sultats obtenus \u00e9taient similaires \u00e0 ceux des souris. Les chercheurs ont \u00e9galement constat\u00e9 que tous ces effets antid\u00e9presseurs aigus<\/strong>, \u00e9valu\u00e9s apr\u00e8s le test de natation 30 minutes apr\u00e8s le traitement, \u00e9taient li\u00e9s \u00e0 la capacit\u00e9 du cannabidiol \u00e0 augmenter les niveaux de BDNF<\/strong>.<\/p>\n Ces niveaux accrus de BDNF \u00e9taient pr\u00e9sents \u00e0 la fois dans l’hippocampe et dans le cortex pr\u00e9frontal des rongeurs. C’est important car le facteur neurotrophique d\u00e9riv\u00e9 du cerveau (BDNF) est un facteur crucial pour la croissance des neurones. De plus, les chercheurs ont \u00e9galement d\u00e9couvert que les marqueurs de la plasticit\u00e9 synaptique<\/strong>, qui sont indispensables au remodelage du cerveau, ont \u00e9galement connu une augmentation dans le cortex pr\u00e9frontal du cerveau.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”4.16″ background_color=”#f3f3f1″ background_enable_image=”off” custom_padding=”21px||18px|||” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”2_5,3_5″ _builder_version=”4.16″ custom_margin=”|auto|-2px|auto||” locked=”off” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/cbd-antidepresivos-largo-plazo.jpg” alt=”antid\u00e9presseurs \u00e0 base de cbd \u00e0 long terme” title_text=”antid\u00e9presseurs \u00e0 base de cbd \u00e0 long terme” align=”center” _builder_version=”4.16″ background_enable_image=”off” background_size=”contain” max_width_phone=”300px” max_width_last_edited=”off|tablet” custom_margin=”|||-30%|false|false” custom_margin_tablet=”|||-15%|false|false” custom_margin_phone=”|||-10%|false|false” custom_margin_last_edited=”on|phone” locked=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding_tablet=”|20%|||false|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ header_2_font=”|800|||||||” header_2_text_color=”#000000″ header_2_font_size=”40px” header_2_line_height=”1.2em” custom_margin=”||||false|false” custom_margin_tablet=”|||0%|false|false” custom_margin_last_edited=”off|desktop” header_2_font_size_tablet=”35px” header_2_font_size_phone=”25px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ text_font_size_tablet=”14px” text_font_size_last_edited=”off|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n Quant aux effets antid\u00e9presseurs du cannabidiol CBD \u00e0 long terme, les scientifiques ont constat\u00e9 qu’ils \u00e9taient associ\u00e9s \u00e0 une am\u00e9lioration de la fonction synaptique dans le cortex pr\u00e9frontal<\/strong>. Il s’agissait du test de natation chez les souris \u00e9valu\u00e9 7 jours apr\u00e8s l’administration de la dose de CBD.<\/p>\n Les r\u00e9sultats soutiennent la th\u00e9orie selon laquelle le cannabidiol CBD extrait du cannabis est en fait un antid\u00e9presseur \u00e0 action rapide. De plus, ses effets antid\u00e9presseurs sont durables. En d’autres termes, la consommation de CBD \u00e0 des doses ad\u00e9quates pourrait entra\u00eener une activit\u00e9 antid\u00e9pressive \u00e0 plus long terme.<\/p>\n Bien que des recherches suppl\u00e9mentaires soient \u00e9videmment n\u00e9cessaires sur le sujet, les r\u00e9sultats de ces \u00e9tudes sugg\u00e8rent que la CBD pourrait \u00eatre un traitement th\u00e9rapeutique prometteur pour les troubles de l’humeur, et plus particuli\u00e8rement la d\u00e9pression.<\/p>\n N’oublions pas que le CBD est d\u00e9j\u00e0 bien connu pour ses bienfaits sur d’autres pathologies telles que la maladie d’Alzheimer, les douleurs chroniques ou les dysfonctionnements neurologiques. Il ne serait donc pas surprenant qu’il ait \u00e9galement un effet positif dans le traitement de la d\u00e9pression.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” admin_label=”Features” _builder_version=”4.16″ background_color=”#f3f3f1″ custom_padding=”0px|0px|0px|0px” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”1″ make_equal=”on” admin_label=”Ligne CTA” module_class=” et_pb_row_fullwidth” _builder_version=”4.16″ width=”100%” width_tablet=”100%” width_phone=”” width_last_edited=”on|desktop” max_width=”100%” max_width_tablet=”100%” max_width_phone=”” max_width_last_edited=”on|desktop” custom_padding=”0px|0px|0px|0px” make_fullwidth=”on” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_enable_image=”off” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/cbd-depresion.jpg” alt=”d\u00e9pr\u00e9sement de cbd” title_text=”d\u00e9pr\u00e9sement de cbd” force_fullwidth=”on” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color=”#00a88d” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_cta title=”Le r\u00f4le du CBD dans la d\u00e9pression” button_url=”#top” _builder_version=”4.16″ header_font=”|800|||||||” header_text_color=”#ffffff” body_font=”Montserrat|500|||||||” body_text_color=”#ffffff” body_link_text_color=”#000000″ use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#ffffff” button_bg_color=”#2f3854″ button_border_width=”10px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”60px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” button_alignment=”left” text_orientation=”left” max_width=”580px” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|desktop” module_alignment=”left” custom_margin=”|||” custom_padding=”40px|60px|2px|60px||” button_text_color_hover=”#2f3854″ button_border_radius_hover=”66px” button_letter_spacing_hover=”1px” button_bg_color_hover=”#ffffff” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”on” button_text_color__hover=”#2f3854″ button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”on” button_border_radius__hover=”66px” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”on” button_letter_spacing__hover=”1px” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#ffffff” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”]Comme nous l’avons mentionn\u00e9 plus haut, les options actuelles de traitement de la d\u00e9pression, qui comprennent l’utilisation de m\u00e9dicaments antid\u00e9presseurs, peuvent \u00eatre probl\u00e9matiques. Ceci est principalement d\u00fb au fait que les patients doivent souvent faire face \u00e0 un retard li\u00e9 \u00e0 ses effets. En ce sens, la CBD pourrait \u00eatre une alternative efficace dans la lutte contre la d\u00e9pression<\/strong>.<\/p>\n Une recherche de 2019, a r\u00e9v\u00e9l\u00e9 que le cannabidiol (CBD) induit des effets similaires aux antid\u00e9presseurs \u00e0 action rapide et prolong\u00e9e<\/a>. Tout cela gr\u00e2ce \u00e0 une augmentation de la signalisation du BDNF et de la synaptogen\u00e8se dans le cortex pr\u00e9frontal du cerveau. Des chercheurs de l’universit\u00e9 de Sao Paulo, au Br\u00e9sil, ont test\u00e9 les effets antid\u00e9presseurs du CBD<\/strong> sur des rats et des souris afin de d\u00e9terminer si ce cannabidiol a un d\u00e9but d’action rapide.<\/p>\n Au cours de la recherche, le CBD a \u00e9t\u00e9 administr\u00e9 en une seule dose dans une quantit\u00e9 qui pouvait \u00eatre de 7, 10 ou 30 mg par kilogramme de poids corporel. Les scientifiques ont ensuite soumis les rongeurs \u00e0 un test de nage forc\u00e9e apr\u00e8s 30 minutes ou jusqu’\u00e0 7 jours apr\u00e8s le d\u00e9but du traitement.[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Subscribe” _builder_version=”4.16″ use_background_color_gradient=”on” background_color_gradient_stops=”#f3f3f1 0%|rgba(255,255,255,0) 30%” background_color_gradient_overlays_image=”on” background_color_gradient_start=”#f3f3f1″ background_color_gradient_end=”rgba(255,255,255,0)” background_color_gradient_end_position=”30%” background_image=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/aceite-de-cannabis-cbd.jpg” custom_padding=”100px|0px|30vw|0px” animation_direction=”bottom” saved_tabs=”all” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”|500|||||||” text_text_color=”rgba(47,56,84,0.5)” text_font_size=”16px” text_line_height=”1.9em” header_font=”||||||||” header_2_font=”|700|||||||” header_2_font_size=”50px” header_2_line_height=”1.3em” text_orientation=”center” max_width=”700px” module_alignment=”center” global_colors_info=”{}”]<\/p>\n Abonnez-vous et b\u00e9n\u00e9ficiez d\u2019une r\u00e9duction de 10% sur votre achat. <\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_2,1_4″ _builder_version=”4.16″ custom_padding=”19px|||||” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_signup mailchimp_list=”higeacbd|5b4d14cf0e” first_name_field=”off” last_name_field=”off” _builder_version=”4.16″ header_font=”||||||||” use_background_color=”off” custom_button=”on” button_text_size=”16px” button_text_color=”#ffffff” button_bg_color=”#00a88d” button_border_width=”10px” button_border_color=”rgba(47,56,84,0)” button_border_radius=”89px” button_letter_spacing=”1px” button_font=”Montserrat|700||on|||||” button_use_icon=”off” border_radii_fields=”on|30px|30px|30px|30px” border_width_all_fields=”1px” border_color_all_fields=”rgba(47,56,84,0.2)” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_signup][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Footer” _builder_version=”4.5.1″ background_color=”#f3f3f1″ background_image=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cannabis-medicinal.jpg” background_size=”contain” background_position=”bottom_center” global_module=”452″ saved_tabs=”all” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ make_equal=”on” _builder_version=”4.16″ 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compagnie CBD” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE4OTgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.16″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Cytokines” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjE5OTkifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.16″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” 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icon_placement=”left” _builder_version=”4.16″ header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Huiles porteuses” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIzNzcifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.16″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Qu\u2019est-ce que les flavono\u00efdes” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIyOTMifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.16″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Effets de cbd” url=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIwNjgifX0=@” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#ffffff” icon_placement=”left” _builder_version=”4.18.0″ _dynamic_attributes=”url” header_font=”|700||on|||||” header_text_color=”#ffffff” header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|phone” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_color=”#ffffff” custom_padding=”80px|60px|80px|60px|true|true” custom_padding_tablet=”50px|30px|50px|30px|true|true” custom_padding_phone=”30px|20px|30px|20px|true|true” custom_padding_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ text_font=”Montserrat|800|||||||” text_font_size=”30px” text_line_height=”1.2em” link_text_color=”#000000″ header_3_font=”|700||on|||||” header_3_text_color=”#000000″ header_3_font_size=”16px” header_3_letter_spacing=”2px” header_3_line_height=”1.8em” header_4_font=”|700|||||||” custom_margin=”||0px||false|false” custom_padding=”10px||10px||true|false” text_font_size_tablet=”22px” text_font_size_phone=”16px” text_font_size_last_edited=”on|desktop” header_3_font_size_tablet=”14px” header_3_font_size_phone=”12px” header_3_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-32-1-1.png” alt=”simboolo higea” title_text=”simboolo higea” _builder_version=”4.16″ locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.16″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n AVIS JURIDIQUE<\/a><\/p>\n [\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.16″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]CONFIDENTIALIT\u00c9 ET COOKIES<\/a>[\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.16″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n POLITIQUE DE RETOUR<\/a><\/p>\n [\/et_pb_blurb][et_pb_blurb url_new_window=”on” use_icon=”on” font_icon=”V||divi||400″ icon_color=”#000000″ icon_placement=”left” _builder_version=”4.16″ header_font=”|700||on|||||” header_text_color=”#000000″ header_font_size=”16px” header_letter_spacing=”2px” header_line_height=”1.8em” body_font=”|700||on|||||” body_text_color=”#000000″ body_font_size=”16px” body_letter_spacing=”2px” body_line_height=”1.8em” custom_margin=”||0px||false|false” animation=”off” link_option_url_new_window=”on” header_font_size_tablet=”14px” header_font_size_phone=”12px” header_font_size_last_edited=”on|desktop” body_font_size_tablet=”14px” body_font_size_phone=”12px” body_font_size_last_edited=”on|desktop” global_colors_info=”{}”]CONTACT<\/a>[\/et_pb_blurb][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font_size=”15px” global_colors_info=”{}”]pedidos@higeacbd.com<\/a>[\/et_pb_text][et_pb_image src=”https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/08\/formas-de-pago.png” alt=”m\u00e9thodes de paiement” title_text=”m\u00e9thodes de paiement” _builder_version=”4.16″ _module_preset=”default” custom_margin=”10px||10px||false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”DMCA protected” _builder_version=”4.16″ _module_preset=”default” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}”] Comment fonctionnent les antid\u00e9presseurs ? Une nouvelle \u00e9tude r\u00e9v\u00e8le la v\u00e9rit\u00e9<\/h2>\n
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Le BDNF et sa relation avec la plasticit\u00e9 neuronale<\/h2>\n
La k\u00e9tamine a un effet antid\u00e9presseur plus rapide<\/h2>\n
Le cholest\u00e9rol pourrait jouer un r\u00f4le cl\u00e9 dans l’action des antid\u00e9presseurs<\/h2>\n
Des recherches suppl\u00e9mentaires sont n\u00e9cessaires sur le cholest\u00e9rol et les antid\u00e9presseurs<\/h2>\n
Pourquoi certains antid\u00e9presseurs agissent-ils plus rapidement que d’autres ?<\/h2>\n
Points cl\u00e9s de la recherche<\/h2>\n
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Effets antid\u00e9presseurs \u00e0 court terme du CBD<\/h2>\n
Effets antid\u00e9presseurs \u00e0 long terme du CBD<\/h2>\n
Abonnez-vous \u00e0 notre newsletter<\/h2>\n
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