{"id":36177,"date":"2021-03-08T18:28:19","date_gmt":"2021-03-08T18:28:19","guid":{"rendered":"https:\/\/higeacbd.com\/olis\/gpr55-un-tercer-receptor-de-cannabinoides\/"},"modified":"2025-03-24T12:05:39","modified_gmt":"2025-03-24T12:05:39","slug":"gpr55-un-tercer-receptor-de-cannabinoides","status":"publish","type":"post","link":"https:\/\/higeacbd.com\/ca\/datos\/gpr55-un-tercer-receptor-de-cannabinoides","title":{"rendered":"GPR55: Un tercer receptor de cannabinoides?"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.9.1&#8243; background_color=&#8221;rgba(255,255,255,0.65)&#8221; background_image=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/gpr55.jpg&#8221; background_blend=&#8221;soft-light&#8221; custom_padding=&#8221;3vw||1vw|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; 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_builder_version=&#8221;4.5.1&#8243; background_color=&#8221;#f3f3f1&#8243; custom_padding=&#8221;20px||11px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.5.1&#8243; custom_padding=&#8221;8px||17px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.5.1&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.1&#8243; text_font=&#8221;|500|||||||&#8221; text_text_color=&#8221;#000000&#8243; quote_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;|800|||||||&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.4em&#8221; max_width=&#8221;80%&#8221; max_width_tablet=&#8221;90%&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||12px|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>La capacitat del <strong>receptor GPR55, que<\/strong>ara es considera el <strong>tercer receptor cannabinoide <a href=\"https:\/\/higeacbd.com\/ca\/datos\/sistema-endocannabinoide\" title=\"Sistema endocannabinoide\">identificat<\/a> <\/strong> en el sistema endocannabinoide hum\u00e0, es va il\u00b7lustrar en un estudi cient\u00edfic del 2018. Es va descobrir que aquest receptor juga un paper clau en el tractament de la s\u00edndrome de Dravet, un tipus rar i greu d&#8217;epil\u00e8psia.<\/p>\n<p>Segons el resum publicat a <a href=\"https:\/\/www.pnas.org\/content\/early\/2017\/09\/26\/1711351114\" target=\"_blank\" rel=\"noopener\">Proceedings of the National Academy of Sciences,<\/a>un grup d&#8217;investigadors de la Universitat de Washington a Seattle va veure potencial<strong>per &#8220;estendre l&#8217;espectre<\/strong>de la ter\u00e0pia de CDB&#8221; a activitats similars a l&#8217;autisme. Aix\u00f2 faria factible proporcionar informaci\u00f3 mecan\u00edstica inicial sobre les accions terap\u00e8utiques del CBD.<\/p>\n<p>Cal dir que els receptors de cannabinoides s\u00f3n mol\u00e8cules de prote\u00efnes complexes, que interactuen amb els compostos actius del c\u00e0nnabis en el cos hum\u00e0, <a href=\"https:\/\/higeacbd.com\/ca\/datos\/sistema-endocannabinoide\" title=\"Sistema endocannabinoide\">en el que es coneix com el sistema endocannabinoide.<\/a><\/p>\n<p>Els cient\u00edfics han estat parlant dels <strong> <a href=\"https:\/\/higeacbd.com\/ca\/beneficis\/lefecte-del-cbd-sobre-el-cervell\" title=\"Efecto del CBD en el cerebro\">receptors CB1 i CB2 des<\/a> <\/strong>de la d\u00e8cada de 1990. No obstant aix\u00f2, la investigaci\u00f3 sobre el receptor GPR55 i el paper que sembla jugar en el sistema endocannabinoide com un altre receptor cannabinoide especial est\u00e0 en les seves primeres etapes.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;Productes&#8221; _builder_version=&#8221;4.7.7&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_module=&#8221;16824&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_shop type=&#8221;best_selling&#8221; posts_number=&#8221;8&#8243; show_pagination=&#8221;on&#8221; module_class=&#8221;custom-shop&#8221; _builder_version=&#8221;4.13.0&#8243; _module_preset=&#8221;default&#8221; title_font=&#8221;|700|||||||&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_shop][et_pb_signup mailchimp_list=&#8221;higeacbd|5b4d14cf0e&#8221; first_name_field=&#8221;off&#8221; last_name_field=&#8221;off&#8221; title=&#8221;Subscriu-te i rep un 10% de descompte&#8221; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.13.0&#8243; header_level=&#8221;h4&#8243; header_font=&#8221;|800|||||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;35px&#8221; header_line_height=&#8221;1.2em&#8221; use_background_color=&#8221;off&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;16px&#8221; button_text_color=&#8221;#00a88d&#8221; button_bg_color=&#8221;rgba(0,0,0,0)&#8221; button_border_width=&#8221;0px&#8221; button_border_radius=&#8221;0px&#8221; button_letter_spacing=&#8221;2px&#8221; button_font=&#8221;|700||on|||||&#8221; button_use_icon=&#8221;off&#8221; button_custom_padding=&#8221;18px|0px|18px|0px|true|true&#8221; button_custom_padding_tablet=&#8221;14px||14px||true|true&#8221; button_custom_padding_phone=&#8221;12px||12px||true|true&#8221; button_custom_padding_last_edited=&#8221;on|phone&#8221; background_layout=&#8221;light&#8221; header_font_size_tablet=&#8221;25px&#8221; header_font_size_phone=&#8221;20px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; button_text_size_tablet=&#8221;14px&#8221; button_text_size_phone=&#8221;12px&#8221; button_text_size_last_edited=&#8221;on|phone&#8221; box_shadow_style_button=&#8221;preset4&#8243; box_shadow_horizontal_button=&#8221;0px&#8221; box_shadow_vertical_button=&#8221;2px&#8221; box_shadow_color_button=&#8221;#00a88d&#8221; global_colors_info=&#8221;{}&#8221; button_text_color__hover=&#8221;#28221d&#8221; button_text_color__hover_enabled=&#8221;on|hover&#8221; box_shadow_color_button__hover=&#8221;#000000&#8243; box_shadow_color_button__hover_enabled=&#8221;on|desktop&#8221;][\/et_pb_signup][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#f3f3f1&#8243; custom_padding=&#8221;14px||27px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;12px||13px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|800|||||||&#8221; header_2_text_align=&#8221;center&#8221; header_2_font_size=&#8221;35px&#8221; header_2_line_height=&#8221;1.2em&#8221; max_width=&#8221;80%&#8221; max_width_tablet=&#8221;90%&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||-5px|||&#8221; custom_padding=&#8221;||0px|||&#8221; header_2_font_size_tablet=&#8221;25px&#8221; header_2_font_size_phone=&#8221;20px&#8221; header_2_font_size_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Els or\u00edgens del tercer receptor cannabinoide GPR55<\/h2>\n<p>El <strong>receptor GPR55 va <\/strong>ser identificat per primera vegada com un &#8220;nou receptor de cannabinoides&#8221; el 2007. Aix\u00f2 va ser en un estudi realitzat i publicat <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2095107\/\" target=\"_blank\" rel=\"noopener\">pel Centre Nacional d&#8217;Informaci\u00f3 Biotecnol\u00f2gica (NCBI).<\/a> Anteriorment es considerava un &#8220;receptor orfe&#8221;, el que significa que <strong>la seva funci\u00f3 exacta no s&#8217;havia determinat.<\/strong><\/p>\n<p>En anys posteriors, l&#8217;evid\u00e8ncia ha acumulat que el receptor GPR55 podria ser responsable de molts dels beneficis documentats dels usuaris de c\u00e0nnabis.<\/p>\n<p>Per exemple, el receptor GPR55 va tenir un paper important en el control de l&#8217;activitat de l&#8217;osteoclast. \u00c9s a dir, en la formaci\u00f3 i curaci\u00f3 \u00f2ssia, que es va revelar <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2737440\/\" target=\"_blank\" rel=\"noopener\">en un estudi de 2009 publicat a PNAS.<\/a> El Centre Nacional d&#8217;Informaci\u00f3 Biotecnol\u00f2gica (NCBI) tamb\u00e9 va publicar un informe el 2016 afirmant que va trobar un paper similar en la gesti\u00f3 de la inflamaci\u00f3.<\/p>\n<p>No nom\u00e9s aix\u00f2, una <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4397721\/\" target=\"_blank\" rel=\"noopener\">investigaci\u00f3 de 2015 sobre Fronteres en Farmacologia va<\/a>trobar que dos receptors orfes, aix\u00ed com el receptor GPR55, poden ser dianes terap\u00e8utiques prometedores. Aix\u00f2 significa que realitzarien diverses funcions fisiol\u00f2giques, que van des de <strong>proporcionar alleujament als trastorns gastrointestinals, fins als<\/strong>trastorns hep\u00e0tics.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Features&#8221; _builder_version=&#8221;4.5.1&#8243; background_color=&#8221;#f3f3f1&#8243; custom_padding=&#8221;0px|0px|0px|0px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; make_equal=&#8221;on&#8221; admin_label=&#8221;Cta Fila&#8221; module_class=&#8221; et_pb_row_fullwidth&#8221; _builder_version=&#8221;4.8.2&#8243; background_color=&#8221;#00a88d&#8221; width=&#8221;100%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;&#8221; width_last_edited=&#8221;on|desktop&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;0px|0px|0px|0px&#8221; make_fullwidth=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.5.1&#8243; background_enable_image=&#8221;off&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2021\/03\/receptor-cannabinoide-GPR55.jpg&#8221; alt=&#8221;Receptor de cannabinoides GPR55&#8243; title_text=&#8221;Receptor de cannabinoides GPR55&#8243; force_fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.9.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.8.2&#8243; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_cta title=&#8221;Qu\u00e8 diu la ci\u00e8ncia sobre el receptor cannabinoide GPR55?&#8221; button_url=&#8221;#top&#8221; _builder_version=&#8221;4.14.5&#8243; header_font=&#8221;|800|||||||&#8221; header_text_color=&#8221;#ffffff&#8221; header_font_size=&#8221;35px&#8221; body_font=&#8221;Montserrat|500|||||||&#8221; body_text_color=&#8221;#ffffff&#8221; body_link_text_color=&#8221;#000000&#8243; use_background_color=&#8221;off&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;16px&#8221; button_text_color=&#8221;#ffffff&#8221; button_bg_color=&#8221;#2f3854&#8243; button_border_width=&#8221;10px&#8221; button_border_color=&#8221;rgba(47,56,84,0)&#8221; button_border_radius=&#8221;60px&#8221; button_letter_spacing=&#8221;1px&#8221; button_font=&#8221;Montserrat|700||on|||||&#8221; button_use_icon=&#8221;off&#8221; button_alignment=&#8221;left&#8221; text_orientation=&#8221;left&#8221; max_width=&#8221;580px&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|desktop&#8221; module_alignment=&#8221;left&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;40px|60px|2px|60px||&#8221; hover_enabled=&#8221;0&#8243; header_font_size_tablet=&#8221;25px&#8221; header_font_size_phone=&#8221;20px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; button_text_color_hover=&#8221;#2f3854&#8243; button_border_radius_hover=&#8221;66px&#8221; button_letter_spacing_hover=&#8221;1px&#8221; button_bg_color_hover=&#8221;#ffffff&#8221; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;on&#8221; button_text_color__hover=&#8221;#2f3854&#8243; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;on&#8221; button_border_radius__hover=&#8221;66px&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;on&#8221; button_letter_spacing__hover=&#8221;1px&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;on&#8221; button_bg_color__hover=&#8221;#ffffff&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Avui se sap <strong>que <a href=\"https:\/\/higeacbd.com\/ca\/enfermedades\/el-cbd-pot-ajudar-a-la-gastritis\" title=\"CBD y gastritis\">el receptor GPR55 est\u00e0 present en el cervell i el tracte gastrointestinal.<\/a> <\/strong> Rep el nom perqu\u00e8 \u00e9s el n\u00famero 55 en una seq\u00fc\u00e8ncia de receptors acoblats a la prote\u00efna G, que tamb\u00e9 inclou receptors CB1 i CB2.  <strong>G significa guanina, que \u00e9s<\/strong>una base de nucle\u00f2tids, i per tant es considera un dels &#8220;blocs de construcci\u00f3&#8221; de l&#8217;ADN.<\/p>\n<p>A causa de la forma en qu\u00e8 <a href=\"https:\/\/higeacbd.com\/ca?p=86723\" title=\"Receptores cannabinoides\">aquests receptors cannabinoides<\/a> interactuen amb les c\u00e8l\u00b7lules, la guanina est\u00e0 associada amb tots ells.<\/p>\n<p>Segons Robert Sindelar, director cient\u00edfic i director de desenvolupament de productes de BAS Research, productor autoritzat de productes cann\u00e0bics, amb seu a Berkeley, Calif\u00f2rnia, el receptor cannabinoide rep la qu\u00edmica i despr\u00e9s envia senyals a c\u00e8l\u00b7lules com neurones.<\/p>\n<p>Segons Sindelar, durant molts anys, la via endocannabinoide ha estat una mena de caixa cargolada, en gran part a causa de les restriccions dels estudis federals&#8221;. Per tant, els <a href=\"https:\/\/higeacbd.com\/ca\/estudis-cientifics-sobre-els-beneficis-del-cbd\" title=\"Estudios cient\u00edficos beneficios CBD\">cient\u00edfics estan comen\u00e7ant a descobrir com aquests receptors de cannabinoides fan el que fan.<\/a><\/p>\n<p>[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#f3f3f1&#8243; custom_padding=&#8221;14px||27px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;12px||13px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.5.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; header_2_font=&#8221;|800|||||||&#8221; header_2_text_align=&#8221;center&#8221; header_2_font_size=&#8221;35px&#8221; header_2_line_height=&#8221;1.2em&#8221; max_width=&#8221;80%&#8221; max_width_tablet=&#8221;90%&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||-5px|||&#8221; custom_padding=&#8221;||0px|||&#8221; header_2_font_size_tablet=&#8221;25px&#8221; header_2_font_size_phone=&#8221;20px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Fins ara s&#8217;ha <strong>sabut que el CBD t\u00e9 un efecte positiu en les persones amb convulsions.<\/strong> No obstant aix\u00f2, fins ara no se sap amb certesa qu\u00e8 fa que aix\u00f2 passi. Els cient\u00edfics estan posant al dia sobre quina experi\u00e8ncia convencional i dades anecd\u00f2tiques els han perm\u00e8s con\u00e8ixer el receptor GPR55.<\/p>\n<h2>La teva relaci\u00f3 amb la s\u00edndrome de Dravet<\/h2>\n<p>Sindelar es refereix a la s\u00edndrome de Dravet, en el sentit que <strong>\u00e9s una condici\u00f3 gen\u00e8tica que anteriorment es considerava incurable.<\/strong> No obstant aix\u00f2, molts pacients han descobert que prendre CDB cada dia \u00e9s la seva \u00fanica font d&#8217;alleujament.<\/p>\n<p>Els investigadors han descobert el mecanisme o mode d&#8217;acci\u00f3 pel qual el CBD envia un missatge a una part del cervell que informa a un nen amb s\u00edndrome de Dravet si ha de tenir o no una convulsi\u00f3.<\/p>\n<p>Com que hi ha un nombre creixent d&#8217;evid\u00e8ncies al voltant del receptor GPR55, incloent un estudi de 2017 que va trobar el paper dels receptors en el tractament de la s\u00edndrome de Dravet, els investigadors estan sota m\u00e9s pressi\u00f3 per continuar investigant el receptor GPR55. Aquest \u00e9s un objectiu potencial per <strong>al tractament de l&#8217;epil\u00e8psia, especialment pel que fa a com interactua amb el CBD.<\/strong><\/p>\n<p>I segons Sindelar, aquestes investigacions tindrien altres implicacions. \u00c9s a dir, la investigaci\u00f3 est\u00e0 revelant el misteri emp\u00edric que envolta el que la gent observa en la realitat o anecd\u00f2ticament.<\/p>\n<p>Aix\u00f2 pot proporcionar la prova necess\u00e0ria per desprogramar aquests productes qu\u00edmics. En molts aspectes, tot aix\u00f2 conduiria a un canvi en la forma en qu\u00e8 els governs classifiquen els cannabinoides. Si es produeixi aquest canvi, aquestes q\u00fcestions es permetrien estudiar encara m\u00e9s. Fins i tot la investigaci\u00f3 sobre cannabinoides seria elegible per al finan\u00e7ament federal.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Feature&#8221; _builder_version=&#8221;4.5.1&#8243; background_color=&#8221;#f3f3f1&#8243; background_enable_image=&#8221;off&#8221; custom_padding=&#8221;40px||40px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;4.4.4&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.4.4&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cbd-aceite-comprar.jpg&#8221; alt=&#8221;efic\u00e0cia del CBD&#8221; title_text=&#8221;Efici\u00e8ncia del CBD&#8221; _builder_version=&#8221;4.9.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.4.4&#8243; custom_padding_tablet=&#8221;|20%|||false|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; header_2_font=&#8221;|800|||||||&#8221; header_2_text_color=&#8221;#000000&#8243; header_2_font_size=&#8221;35px&#8221; header_2_line_height=&#8221;1.2em&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;|||0%|false|false&#8221; custom_margin_last_edited=&#8221;off|desktop&#8221; header_2_font_size_tablet=&#8221;25px&#8221; header_2_font_size_phone=&#8221;20px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>GPR55 podria ser la clau de l&#8217;efic\u00e0cia del CBD<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font_size_tablet=&#8221;14px&#8221; text_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>El CBD ha augmentat en popularitat i acceptaci\u00f3 en els \u00faltims anys com un cannabinoide no psicoactiu. A m\u00e9s, se sap que t\u00e9 una gran varietat d&#8217;aplicacions medicinals.<\/p>\n<p>S&#8217;han investigat les seves propietats antitor tumorals, anticonvulsives i antiinflamat\u00f2ries, amb resultats prometedors. Com <strong>que el CBD no ha mostrat cap afinitat pels receptors CB1 i CB2,<\/strong>es creu que funciona a trav\u00e9s d&#8217;altres vies. Tot indica que el cannabinoide \u00e9s atret pels receptors vainil\u00b7lars i el receptor 5-HT1A.<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Feature&#8221; _builder_version=&#8221;4.5.1&#8243; background_color=&#8221;#f3f3f1&#8243; background_enable_image=&#8221;off&#8221; custom_padding=&#8221;21px||18px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_5,3_5&#8243; _builder_version=&#8221;4.5.1&#8243; custom_margin=&#8221;|auto|-2px|auto||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.5.1&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/cual-es-el-mejor-aceite-de-cbd.jpg&#8221; alt=&#8221;neurog\u00e8nesi thc cbd&#8221; title_text=&#8221;Neurog\u00e8nesi del THC CBD&#8221; align=&#8221;center&#8221; _builder_version=&#8221;4.5.1&#8243; background_enable_image=&#8221;off&#8221; background_size=&#8221;contain&#8221; max_width_phone=&#8221;300px&#8221; max_width_last_edited=&#8221;off|tablet&#8221; custom_margin=&#8221;|||-30%|false|false&#8221; custom_margin_tablet=&#8221;|||-15%|false|false&#8221; custom_margin_phone=&#8221;|||-10%|false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.4.4&#8243; custom_padding_tablet=&#8221;|20%|||false|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font_size_tablet=&#8221;14px&#8221; text_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Altres cannabinoides tamb\u00e9 s&#8217;han demostrat que s&#8217;uneixen al receptor GPR55, per\u00f2 en aquests casos el CBD inhibeix la seva funci\u00f3. Aix\u00f2 podria explicar alguns dels seus beneficis medicinals.<\/p>\n<p>A m\u00e9s, gpr55 es creu que juga un paper important en el c\u00e0ncer durant la investigaci\u00f3 in vitro primerenca. El potencial invasiu de les c\u00e8l\u00b7lules metast\u00e0tiques, aix\u00ed com el desenvolupament de met\u00e0stasis \u00f2ssies en diversos tipus de tumors estan relacionats amb la senyalitzaci\u00f3 GPR55.<\/p>\n<p>La senyalitzaci\u00f3 GPR55 tamb\u00e9 ha estat vinculada a la progressi\u00f3 del c\u00e0ncer, especialment quan es tracta de malalties limfol\u00f2giques.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Art\u00edculos relacionados blog&#8221; _builder_version=&#8221;4.7.0&#8243; background_color=&#8221;#f3f3f1&#8243; background_enable_image=&#8221;off&#8221; custom_padding=&#8221;21px||9px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.5.1&#8243; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;11px||7px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; 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include_categories=&#8221;current&#8221; show_more=&#8221;on&#8221; show_author=&#8221;off&#8221; show_date=&#8221;off&#8221; _builder_version=&#8221;4.7.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Subscribe&#8221; _builder_version=&#8221;4.5.1&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_start=&#8221;#f3f3f1&#8243; background_color_gradient_end=&#8221;rgba(255,255,255,0)&#8221; background_color_gradient_end_position=&#8221;30%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/aceite-de-cannabis-cbd.jpg&#8221; custom_padding=&#8221;100px|0px|30vw|0px&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_duration=&#8221;1250ms&#8221; animation_intensity_slide=&#8221;1%&#8221; 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global_colors_info=&#8221;{}&#8221;][\/et_pb_blurb][et_pb_blurb title=&#8221;Qu\u00e8 s\u00f3n els flavonoides&#8221; url=&#8221;@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjIyOTMifX0=@&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x56;||divi||400&#8243; icon_color=&#8221;#ffffff&#8221; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.13.0&#8243; _dynamic_attributes=&#8221;url&#8221; header_font=&#8221;|700||on|||||&#8221; header_text_color=&#8221;#ffffff&#8221; header_font_size=&#8221;16px&#8221; header_letter_spacing=&#8221;2px&#8221; header_line_height=&#8221;1.8em&#8221; custom_margin=&#8221;||0px||false|false&#8221; animation=&#8221;off&#8221; header_font_size_tablet=&#8221;14px&#8221; header_font_size_phone=&#8221;12px&#8221; header_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.4.9&#8243; 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text_font_size_phone=&#8221;16px&#8221; text_font_size_last_edited=&#8221;on|desktop&#8221; header_3_font_size_tablet=&#8221;14px&#8221; header_3_font_size_phone=&#8221;12px&#8221; header_3_font_size_last_edited=&#8221;on|phone&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h4>Av\u00eds legal i pol\u00edtica de privacitat<\/h4>\n<p>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/higeacbd.com\/wp-content\/uploads\/2020\/07\/spice-shop-32-1-1.png&#8221; alt=&#8221;Simbolo higea (A prop de Simbolo higea)&#8221; title_text=&#8221;Simbolo higea (A prop de Simbolo higea)&#8221; _builder_version=&#8221;4.5.1&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_blurb url_new_window=&#8221;on&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x56;||divi||400&#8243; icon_color=&#8221;#000000&#8243; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.13.0&#8243; header_font=&#8221;|700||on|||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;16px&#8221; header_letter_spacing=&#8221;2px&#8221; header_line_height=&#8221;1.8em&#8221; body_font=&#8221;|700||on|||||&#8221; body_text_color=&#8221;#000000&#8243; body_font_size=&#8221;16px&#8221; body_letter_spacing=&#8221;2px&#8221; body_line_height=&#8221;1.8em&#8221; custom_margin=&#8221;||0px||false|false&#8221; animation=&#8221;off&#8221; link_option_url_new_window=&#8221;on&#8221; header_font_size_tablet=&#8221;14px&#8221; header_font_size_phone=&#8221;12px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; body_font_size_tablet=&#8221;14px&#8221; body_font_size_phone=&#8221;12px&#8221; body_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/higeacbd.com\/ca\/avis-legal-i-condicions-generals\" target=\"_blank\" rel=\"noopener nofollow\">AV\u00cdS LEGAL<\/a><\/p>\n<p>[\/et_pb_blurb][et_pb_blurb url_new_window=&#8221;on&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x56;||divi||400&#8243; icon_color=&#8221;#000000&#8243; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.13.0&#8243; header_font=&#8221;|700||on|||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;16px&#8221; header_letter_spacing=&#8221;2px&#8221; header_line_height=&#8221;1.8em&#8221; body_font=&#8221;|700||on|||||&#8221; body_text_color=&#8221;#000000&#8243; body_font_size=&#8221;16px&#8221; body_letter_spacing=&#8221;2px&#8221; body_line_height=&#8221;1.8em&#8221; custom_margin=&#8221;||0px||false|false&#8221; animation=&#8221;off&#8221; link_option_url_new_window=&#8221;on&#8221; header_font_size_tablet=&#8221;14px&#8221; header_font_size_phone=&#8221;12px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; body_font_size_tablet=&#8221;14px&#8221; body_font_size_phone=&#8221;12px&#8221; body_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/higeacbd.com\/ca\/politica-de-privacitat-i-avis-sobre-les-cookies\" target=\"_blank\" rel=\"noopener nofollow\">PRIVACITAT I COOKIES<\/a>[\/et_pb_blurb][et_pb_blurb url_new_window=&#8221;on&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x56;||divi||400&#8243; icon_color=&#8221;#000000&#8243; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.13.0&#8243; header_font=&#8221;|700||on|||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;16px&#8221; header_letter_spacing=&#8221;2px&#8221; header_line_height=&#8221;1.8em&#8221; body_font=&#8221;|700||on|||||&#8221; body_text_color=&#8221;#000000&#8243; body_font_size=&#8221;16px&#8221; body_letter_spacing=&#8221;2px&#8221; body_line_height=&#8221;1.8em&#8221; custom_margin=&#8221;||0px||false|false&#8221; animation=&#8221;off&#8221; link_option_url_new_window=&#8221;on&#8221; header_font_size_tablet=&#8221;14px&#8221; header_font_size_phone=&#8221;12px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; body_font_size_tablet=&#8221;14px&#8221; body_font_size_phone=&#8221;12px&#8221; body_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/higeacbd.com\/ca\/politica-de-devolucions\" target=\"_blank\" rel=\"noopener nofollow\">POL\u00cdTICA DE DEVOLUCIONS<\/a><\/p>\n<p>[\/et_pb_blurb][et_pb_blurb url_new_window=&#8221;on&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x56;||divi||400&#8243; icon_color=&#8221;#000000&#8243; icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.13.0&#8243; header_font=&#8221;|700||on|||||&#8221; header_text_color=&#8221;#000000&#8243; header_font_size=&#8221;16px&#8221; header_letter_spacing=&#8221;2px&#8221; header_line_height=&#8221;1.8em&#8221; body_font=&#8221;|700||on|||||&#8221; body_text_color=&#8221;#000000&#8243; body_font_size=&#8221;16px&#8221; body_letter_spacing=&#8221;2px&#8221; body_line_height=&#8221;1.8em&#8221; custom_margin=&#8221;||0px||false|false&#8221; animation=&#8221;off&#8221; link_option_url_new_window=&#8221;on&#8221; header_font_size_tablet=&#8221;14px&#8221; header_font_size_phone=&#8221;12px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; body_font_size_tablet=&#8221;14px&#8221; body_font_size_phone=&#8221;12px&#8221; body_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<a href=\"https:\/\/higeacbd.com\/ca\/contacte\" target=\"_blank\" rel=\"noopener nofollow\">Contacte<\/a>[\/et_pb_blurb][et_pb_text _builder_version=&#8221;4.6.5&#8243; 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url=&#8221;https:\/\/www.pinterest.es\/higeacbd\/&#8221; _builder_version=&#8221;4.6.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#cb2027&#8243; global_colors_info=&#8221;{}&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]pinterest[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=&#8221;twitter&#8221; url=&#8221;https:\/\/twitter.com\/higeacbd&#8221; _builder_version=&#8221;4.6.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#00aced&#8221; global_colors_info=&#8221;{}&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]twitter[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n<span class=\"et_bloom_bottom_trigger\"><\/span>","protected":false},"excerpt":{"rendered":"<p>GPR55 \u00e9s considerat el tercer receptor de cannabinoides en el nostre sistema endocanabinoide. 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